MRI feature of meningeal metastasis and correlation of peritumoral brain edema and VEGF expression
10.3760/cma.j.issn.1008-6706.2015.07.016
- VernacularTitle:脑膜转移瘤磁共振影像学特征及其瘤周水肿与血管内皮生长因子表达相关性分析
- Author:
Laihua XIAO
;
Jiwei YU
- Publication Type:Journal Article
- Keywords:
Meningeal metastasis;
Vascular endothelial growth factor;
Peritumoral brain edema
- From:
Chinese Journal of Primary Medicine and Pharmacy
2015;(7):1009-1010,1011
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the MRI feature of meningeal metastasis and correlation of peritumoral brain edema and vascular endothelial growth factor(VEGF)expression.Methods 48 patients with meningeal metas-tasis were observed with plain and enhanced 1 .5 T magnetic resonance imaging scans,surgical removal of the tumor tissues was measured with VEGF immunohistochemistry.Results The patients with MC showed three types MRI fea-ture.The more vascular endothelial growth factor of the tumor tissues expressed,the more peritumoral brain edema (χ2 =33.34,P<0.01 ).Conclusion MRI scanning is necessary for clinical diagnosis in MC.There are positive correlation between the expression of vascular endothelial growth factor of the tumor tissues and peritumoral brain edema(P<0.01).
