Effect of naloxone combined with Buyanghuanwu decoction on congnitive function of multi-infarct dementia patients
10.3760/cma.j.issn.1008-6706.2015.05.001
- VernacularTitle:纳洛酮配合补阳还五汤加减治疗老年人脑梗死性痴呆的临床观察
- Author:
Baohua LIU
;
Guanghui BAI
;
Zhiyi WANG
;
Haiyan LIN
;
Ping SHANG
;
Wei WU
- Publication Type:Journal Article
- Keywords:
Dementa,multi-infarct;
Buyanghuanwu decoction;
Naloxone
- From:
Chinese Journal of Primary Medicine and Pharmacy
2015;(5):641-642,643
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the efficacy of naloxone combined with Buyanghuanwu decoction on cong -nitive function of multi -infarct dementia(MID) patients.Methods 46 patients with MID were treated with Nalox-one Hydrochloride and Buyanghuanwu decoction .Mini -mental state examination ( MMSE ) , activity of daily living ( ADL) scale and hachinski ischemic scale score ( HIS) were used to estimate the therapeutic effect after the treatment for 30 days.Results Compared to 30 days before,the MMSE score and ADL score improved after the treatment (t=3.247,3.469,all P<0.05),and the score of HIS declined (t=3.384,P<0.05).Conclusion Application of nal-oxone combined with Buyanghuanwu decoction can significantly improve congnitive level and ADL function in multi -infarct dementia patients .