Analysis on effect and safety of different doses of propofol for preventing pediatric postoperative agitation
10.3969/j.issn.1671-8348.2015.10.011
- VernacularTitle:不同剂量丙泊酚预防小儿术后躁动的效果和安全性分析
- Author:
Xiaoyan ZENG
;
Li WANG
- Publication Type:Journal Article
- Keywords:
child;
postoperative period;
dysphoria;
propofol;
different doses;
treatment outcome
- From:
Chongqing Medicine
2015;(10):1328-1329,1333
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effects of the different doses of propofol for preventing postoperative agitation in chil-dren.Methods 60 children cases undergoing elective indirect inguinal hernia hernioplasty were selected in the Affiliated Hospital of Traditional Chinese Medicine,Luzhou Medical College from June 2011 to April 2011 and randomly divided into the group Ⅰ,Ⅱ andⅢ.The three groups were performed the general anesthesia with sevoflurane and postoperatively given 0.90% sodium chloride in-jection 0.10 mL/kg by intravenous injection,propofol 1.00 mg/kg by once intravenous injection and propofol 1.00 mg/kg by twice intravenous injection,respectively.The occurrence rate of postoperative agitation within 30 min was compared among 3 groups.The anesthesia recovery agitation score,improved Aldrete score,awakening time and time out of the operation room were also compared. Results The occurrence rates of agitation within postoperative 30 min in the group Ⅰ,Ⅱ and Ⅲ were 65.00%,65.00% and 15.00% respectively,the difference among three groups was statistically significant (P <0.05);the anesthesia recovery agitation score,improved Aldrete score and awakening time had statistically significant differences among 3 groups (P <0.05),the time out of the operation room had no statistical difference(P > 0.05).Conclusion Postoperative twice intravenous injection of propofol 1.00 mg/kg has obvious effect and good safety for preventing the postoperative agitation in children,which has important clinical reference value.
