Analysis of the results of 838 cases of myocardial injury markers in neonates
10.3760/cma.j.issn.1008-6706.2015.11.010
- VernacularTitle:新生儿心肌损伤标志物检测838例结果分析
- Author:
Dexing LUO
;
Kun SHI
;
Yu FANG
;
Guang YUE
;
Yiting DU
;
Chenggui LIU
;
Dengcheng CAO
- Publication Type:Journal Article
- Keywords:
Myocardial injury markers;
hypersensitivitycardiac troponin I
- From:
Chinese Journal of Primary Medicine and Pharmacy
2015;(11):1632-1634,1635
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the diagnostic value and significance of myocardial injury markers in neonates.Methods A retrospective analysis of 838 cases of myocardial injury markers in neonates,the total positive rate of hs -cTnI and the positive rates of hs -cTnI(hypersensitivity cardiac troponin I)in different kinds of neonatal disease were calculated,the levels of abnormalities consistent rate in hs -cTnI and CK -MBmass(creatine kinase MB mass)were compared with hs -cTnI and MYO(Myoglobin).Results The total positive rate of hs -cTnI was 40.33% in the 838 neonates.The highest incidence of myocardial injury was neonatal sepsis (57.14%),followed by neonatal pulmonary hemorrhage (55.56%)and neonatal convulsions (54.55%).The abnormalities consistent rate of hs -cTnI and CK -MBmass was better than hs -cTnI and MYO (85.50% vs 28.11%,χ2 =226.9,P <0.05). Conclusion Neonatal hospitalized children often complicated by myocardial injury;As a biochemical myocardial injury marker,the hs -cTnI detection is important for early detection of myocardial injury,it should be recommend as routine test items;CK -MBmass has better correlation with hs -cTnI than MYO,which can provide guide for doctors to interpret the data of myocardial injury markers.
