Study on effect of brain injury factor in patients with acute cerebral infarction by Ginkgetin injection
- VernacularTitle:银杏叶黄酮注射液对ACI患者脑损伤因子影响研究
- Author:
Lei ZHAO
;
Li MOU
;
Yanqing LIU
;
Wentao LI
- Publication Type:Journal Article
- Keywords:
ginkgetin injection;
acute cerebral infarction;
MESS HIF-1α;
TNF-α;
caspase-3
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;37(5):150-152,155
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore effect of ginkgetin injection on brain damage factor in patients with acute cerebral infarction.Methods 180 cases of acute cerebral infarction patients were selected from June 2014 to February 2015, and divided into experiment group and control group.88 cases in control group were treated with clinical routine therapy, 92 cases in experimental group were treated on base of the control with ginkgetin injection, 2 weeks for a course.The clinical efficacy, MESS and serum HIF-1α, TNF-α, Caspase-3, were detected and compared.Results The clinical efficacy of the experiment group was better than that of control group(P<0.05),and the MESS of the experiment group was lower than the control group(P<0.05).Serum HIF-1α, Caspase-3, TNF-αlevels were lower than the control group(P<0.05).Conclusion Ginkgetin injection can effectively improve the patient’s neurological symptoms, it is of great significance to the clinical treatment of cerebral infarction.
