Comparing the estimated glomerular filtration rate through different equations in evaluating kidney function of the population
10.3969/j.issn.1673-4130.2015.10.022
- VernacularTitle:不同方程估算的肾小球滤过率在人群肾功能评价中的差异比较
- Author:
Lishan SUN
;
Liu LU
;
Mingdong WANG
;
Lin LU
;
Ming YU
;
Lieying FAN
- Publication Type:Journal Article
- Keywords:
glomerular filtration rate;
estimated glomerular filtration rate equations;
estimated glomerular filtration rate
- From:
International Journal of Laboratory Medicine
2015;(10):1370-1372,1375
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the difference of kidney function evaluated by using 3 different estimated glomerular filtration rate(GFR) equations in populations .Methods Retrospectively analyzed 65 856 patients who measured serum creatinine and Cysta‐tin C at the same time ,and come from the outpatients or inpatients of the hospital .The estimated GFR (eGFR) were calculated through 3 equations ,then compared the eGFR in the population and among different groups according to different kidney functions , and then grouped the people enrolled in the study again according to the eGFR calculated by using the 3 different equations and compared the differences among groups .Results Compared with the eGFR calculated by using Creatinine equation ,the correlation coefficients of the eGFRs calculated by using the other two equations were 0 .81 and 0 .90 ,respectively ,both P<0 .05 ;The differ‐ence between the means of eGFR were 6 .19 and 1 .79 mL/(min × 1 .73 m2 ) respectively with obvious significance (P<0 .01) ,in consistency analysis .There were obvious overestimation of kidney function when using Creatinine equation to calculate eGFR .Con‐clusion There is consistence and obvious difference by using the 3 CKD‐EPI′s eGFR equations .Physicians should choose suitable equations to evaluate kidney function in different populations .
