Diagnostic significance of combined detection of tumor markers in breast cancer
10.3969/j.issn.1673-4130.2015.10.038
- VernacularTitle:多指标联合检测对乳腺癌的诊断价值
- Author:
Qiang LI
- Publication Type:Journal Article
- Keywords:
breast cancer;
tumor specific grow th factor;
lysophosphatidic acid;
carbohydrate antigen 153
- From:
International Journal of Laboratory Medicine
2015;(10):1407-1407,1409
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the diagnostic significance of lysophosphatidic acid (LPA) ,tumor specific growth factor (TSGF) and carbohydrate antigen 153 (CA153) in breast cancer .Methods Serum levels of LPA ,TSGF and CA153 were detected in 97 cases of breast cancer (cancer group) ,43 cases of benign breast disease (benign group) and 50 healthy females (control group) .Diagnostic significances of these parameters were analyzed .Results Serum levels of LPA ,TSGF and CA153 in cancer group were significantly higher than benign group and control group (P<0 .05) .Diagnostic sensitivity and specificity of combined detection of LPA ,TSGF and CA153 was higher than individual testing (P<0 .05) .Conclusion Combined detection of tumor mark‐ers could improve the diagnostic specificity and sensitivity of breast cancer ,and provide reliable experimental basis for diagnosis .
