Clinicopathological Characteristics of Postoperative Hepatic Metastasis from Pancreatic Cancer
- VernacularTitle:胰腺癌术后肝转移的临床病理学特点
- Author:
Wei GAO
;
Weiwei SHENG
;
Ming DONG
;
Jianping ZHOU
- Publication Type:Journal Article
- Keywords:
pancreatic cancer;
hepatic metastasis
- From:
Journal of China Medical University
2015;(7):644-647,665
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the incidence of postoperative hepatic metastasis,clinicolpathological characteristics and the prognosis for pancreatic cancer. Methods Totally 83 cases with pancreatic cancer admitted in our hospital during January 2007 to September 2012 was retro?spectively analyzed according to clinicolpathological data. Results Postoperative liver metastasis occurred in 31 cases with a metastatic rate of 37.3%. The size(χ2=9.606;P=0.002),vascular invasion(χ2=4.794,P=0.029)and UICC stage(χ2=5.318,P=0.021)were correlated with he?patic metastasis. Univariate analysis revealed the poor prognosis in pancreatic cancer patient with hepatic metastasis(χ2=9.967,P=0.002). Cox re?gression analysis revealed hepatic metastasis as an independent prognostic factor(P=0.001). Conclusion Pancreatic cancer has a high possibility of hepatic metastasis. Postoperative hepatic metastasis was one of the independent factors for the prognosis of pancreatic cancer. Tumor size,vascular invasion and UICC stages were risk factors for postoperative liver metastasis of pancreatic cancer.