Study of two methods for three hemolytic tests of hemolytic disease of newborn

VernacularTitle:两种方法检测新生儿溶血病“三项试验”的效果比较
Author: Feixiang REN ; Sumei SUN
Publication Type:Journal Article
Keywords: Hemolytic Hisease of Newborn; Microcolumn Gel Test; Tube Anti -Globulin Test
From: Chinese Journal of Primary Medicine and Pharmacy 2015;(10):1493-1495,1496
CountryChina
Language:Chinese
Abstract: Objective To compare and anlyze the applications of microcolumn gel test (MGT)and the tube anti -globulin test (TAT)for detection of three hemolytic tests.Methods Microcolumn gel test and tube anti -globulin test were used in three tests with a total of 160 cases of blood speciments of newborn who had blood group in-compatibility with their mothers:direct anti -globulin test,free test and elution test,then the data were analyzed statis-tically.Results The positive rates of direct anti -globulin test of MGT and TAT were 30.0% and 12.5%(χ2 =14.64,P <0.05);The positive rates of free test of MGT and TAT were 47.5% and 25.0%(χ2 =17.53,P <0.05), respectively;The positive rates of elution test of MGT and TAT were 62.5% and 30.0%(χ2 =33.99,P <0.05). There was statistically significant difference between two methods in three tests.Conclusion MGT has the advantages of quickness,simplicity,high sensitivity,convenience,needs less sample,high repeatability,direct judging of the re-sults,which is better than TAT in three hemolytic tests.