Efficacy of montelukast sodium chewable tablets combined with Tongqiaobiyan particles in the treatment of 48 children with allergic rhinitis
10.3760/cma.j.issn.1008-6706.2015.10.027
- VernacularTitle:孟鲁斯特钠咀嚼片联合通窍鼻炎颗粒治疗儿童过敏性鼻炎48例临床观察
- Author:
Furong LI
- Publication Type:Journal Article
- Keywords:
Rhinitis;
Anaphylaxis;
Montelukast;
Medicine,Chinese Traditional;
Child
- From:
Chinese Journal of Primary Medicine and Pharmacy
2015;(10):1524-1526,1527
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of montelukast sodium chewable tablets joint Tongqiaobiyan particles in the treatment of children with allergic rhinitis.Methods 108 children with allergic rhinitis according to the methods were divided into A group and B group,54 cases in each group.Both A and B group were given Tongqiaobiyan particles,weight <25kg patients,each half bag(1g),3 times a day;weight >25kg patients,each bag, 3 times a day.At the same time the A group was given montelukast sodium chewable tablets:2 to 5 years old,each 4mg,once daily.6 to 14 years old,each 5mg,once daily.Period of treatment for two weeks.Total efficiency and snee-zing,nasal congestion,runny nose,itchy nose symptoms and dry cough improve time,the recurrence rate after one month,two months of the two groups were compared.Results After the treatment,94 cases were accomplished,falled off in 14 cases.Among them,the A group completed in 48 cases,falled off in 6 cases;The B group completed in 46 patients from,falled off in 8 cases.The total effective rate of the A group was 95.8%,which was significantly high-er than 78.3% in the B group(χ2 =6.513,P <0.05).The sneezing,nasal congestion,runny nose,nasal itching and dry caugh of the A group were relieved more significantly than the B group(t =2.628,3.30,2.74,3.58,3.09,all P <0.05).Followed up 1 month and 2 months,the recurrence rates of A group and B group were 6.5% and 20%, 15.2% and 25%,respectively,there were no significant difference between with the two groups(χ2 =1.122,1.338, all P >0.05).Conclusion Tongqiaobiyan particles jointly montelukast sodium chewable tablets integrative curative in treatment of allergic rhinitis can significantly improve clinical symptoms,and has no significant adverse reactions. This method should be popularized and applied.
