Effectiveness of early goal-directed fluid therapy with fresh frozen plasma for severe acute pancre-atitis
10.3969/j.issn.1005-6483.2015.01.011
- VernacularTitle:新鲜冰冻血浆强化早期目标导向液体复苏对重症急性胰腺炎疗效分析
- Author:
Yang ZHANG
;
Xun CAI
;
Jiaxin YE
- Publication Type:Journal Article
- Keywords:
fresh frozen plasma;
EGDT;
severe acute pancreatitis
- From:
Journal of Clinical Surgery
2015;(1):30-32,35
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of early goal-directed fluid therapy with fresh frozen plasma in severe acute pancreatitis(SAP). Methods From January 2010 to June 2014,79 SAP patients were enrolled according to the continuous sampling method. All the patients were randomly divided into a control group who accept the traditional fluid therapy(group A),an experimental group 1 who accept early goal-directed fluid therapy(group B),and an experimental group 2 who accept the early goal-directed fluid therapy with fresh frozen plasma(group C). There were no significant differences of general conditions a-mong groups. The differences of ICU admission,mortality and occurrence rate of abdominal compartment syndrome(ACS)and MODS were compared among groups. Results Compared with group A,group B and C have a shorter length of ICU admission,a lower mortality and a lower occurrence rate of ACS and MODS (P < 0. 05). Compared with group B,group C have a shorter length of ICU admission,a lower mortality and a lower occurrence rate of ACS and MODS(P < 0. 05). Conclusion The method of early goal-direct-ed fluid therapy with fresh frozen plasma will contribute to shorten the length of ICU admission and reduce mortality and occurrence rate of ACS and MODS for patients with SAP.
