Epidemiological survey on related risk factors of newborn infant with Down′s syndrome in Sanya city
10.3969/j.issn.1671-8348.2015.02.031
- VernacularTitle:三亚地区新生儿唐氏综合征流行病学调查及相关发病因素研究
- Author:
Yufeng WANG
;
Yiju YANG
;
Ling LIN
;
Yong WU
;
Qinglan TANG
;
Zhiang ZHENG
;
Xiujuan TIAN
;
Zhixia LI
;
Shaoqing SUN
;
Jihong DAI
;
Xiaowei XING
- Publication Type:Journal Article
- Keywords:
infant,newborn;
Down syndrome;
incidence
- From:
Chongqing Medicine
2015;(2):235-236,240
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the incidence of live births with Down syndrome(DS) in Sanya city as well as to discuss the related risk factors .Methods The object of investigation was the 25 032 infants who were born in Sanya city ,then the children with clinical suspected of DS were confirmed by peripheral blood chromosome analysis .Meanwhile ,the clinical data of children and their parents were collected ,calculating the incidence of DS in this region and analyzing the related risk factors .Results In this region , the total incidence of DS was 0 .959‰ ,the incidences in the Han nationality and Li nationality were 0 .834‰ ,1 .442‰ respectively . The mean age of DS children′s mother was 29 .8 years old ,and the incidence of DS increased as their mother grew older .Before pregnancy ,DS children′s mother who had an exposure history of toxicant and drugs accounted for 45 .8% .Conclusion The inci‐dence of DS in Sanya is quite high ,so it is extremely essential to strengthen the women′s pregnancy Down syndrome screening and improve the prenatal diagnosis in this region .
