Roles of monoamine neurotransmitters in the mechanism of drug addiction
10.3969/j.issn.1001-1978.2015.02.001
- VernacularTitle:单胺类神经递质在药物成瘾中的作用机制
- Author:
Lihua YANG
;
Jie BAI
- Publication Type:Journal Article
- Keywords:
drug addiction;
monoamine neurotransmitter;
5-hydroxytryptamine;
norepinephrine;
dopamine;
brain reward system
- From:
Chinese Pharmacological Bulletin
2015;(2):149-151,152
- CountryChina
- Language:Chinese
-
Abstract:
Drug addiction is a chronic recrudescent brain dis-ease. Various addictive drugs acting on the reward system result in rewarding effects through changes in neurotransmitter patholog-ical release. Among these monoamine neurotransmitters, 5-hydroxytryptamine, norepinephrine and dopamine play key roles in drug addiction. This paper reviews, from a comprehensive perspective, the roles which monoamine neurotransmitters play in the drug addiction and the process of getting addictive.
