Research progress of inflammation reaction related to endoplasmic reticulum stress in ischemic endoplasmic reticulum stress
10.3969/j.issn.1001-1978.2015.01.006
- VernacularTitle:缺血性脑中风中与内质网应激相关炎症反应研究进展
- Author:
Zhiying HUANG
;
Xiaoxu ZHANG
;
Wenli SUN
;
Chang CHEN
;
Defeng LI
;
Jing FANG
;
Meihong FU
;
Qingshan LIU
;
Tianhua YAN
;
Shaojing LI
- Publication Type:Journal Article
- Keywords:
ischemic stroke;
neuron injury;
microenvironment;
endoplasmic reticulum stress;
inflammation;
related signal path-ways
- From:
Chinese Pharmacological Bulletin
2015;(1):23-25,26
- CountryChina
- Language:Chinese
-
Abstract:
Endoplasmic reticulum plays a key role in both basic structure formation and function performance of microenviron-ment. Endoplasmic reticulum homeostasis unbalance caused by endoplasmic reticulum stress has become a hot research topic in recent years. This paper focuses on the role of endoplasmic retic-ulum stress in ischemic stroke. Research progress of related sig-naling pathways were reviewed, especially mechanisms through which endoplasmic reticulum stress trigger the inflammatory reac-tion, so as to provide a new research method for prevention of is-chemic stroke.
