Relevance theories about tumor stem cells and occurrence and metastasis of tumors:recent progress
10.7644/j.issn.1674-9960.2014.12.018
- VernacularTitle:肿瘤干细胞及肿瘤发生与转移新进展
- Author:
Lei ZHOU
;
Shunchang JIAO
- Publication Type:Journal Article
- Keywords:
neoplastic stem cells;
tumor microenvironment;
occurrence;
neoplasm metastasis
- From:
Military Medical Sciences
2014;(12):994-996,999
- CountryChina
- Language:Chinese
-
Abstract:
Tumor stem cells (TSCs) are a group of cells which have self-renewal and differentiation potential in tumor tissues.TSCs not only play an important role in the occurrence and development in tumors , but also are closely related to tumors′invasion,metastasis,heterogeneity and chemo-resistance.Further research of TSCs has become a hot spot .This review intends to explain the formation of TSCs ,the relationship between TSCs and the microenvironment , as well as the model of the TSC microenvironment .Signalling pathways and regulatory factors of TSCs are also discussed .
