Clinical application of combined detection of three indicators in pulmonary tuberculosis patients accompanied with infection
10.3969/j.issn.1673-4130.2015.03.027
- VernacularTitle:肺结核合并感染患者3项指标联合检测的临床应用
- Author:
Meichun LIU
;
Aihua ZHAO
;
Shihua YIN
- Publication Type:Journal Article
- Keywords:
pulmonary tuberculosis;
endotoxin;
procalcitionin;
(1-3)-β-D-glucan
- From:
International Journal of Laboratory Medicine
2015;(3):350-351,354
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical significance of the three indicators combined detection that plasma endotoxin,pro-calcitonin (PCT)and (1,3)-β-D-glucan(BG)in pulmonary tuberculosis patients complicated with bacterial,fungal infection.Methods Retrospective investigation was conducted in 240 pulmonary tuberculosis patients,who were divided into gram negative bacteria (G- )group(39cases),gram positive bacteria (G+ )group(45 cases)including fungal,germ-free group(156 cases).Other 45 healthy people were selected into control group.The levels of plasma endotoxin,PCT and BG in the four groups were compared.Results The levels of plasma endotoxin(0.682±0.418)EU/mL,PCT(2.93±0.87)μg/L in the G- group were significant higher than those of the G+ group (0.063±0.034)EU/mL,(0.85±0.52)μg/L,the difference was significant (P <0.05).The levels of the plasma endotoxin,PCT in the G- group were higher than those of the germ-free group.The levels of plasma endotoxin,PCT and BG in the control group had no significant difference with those of the germ-free group.Conclusion The combined detection of plasma endo-toxin,PCT and BG have some clinical value on the early diagnosis of the patients with pulmonary tuberculosis complicated with G-fungal infection for the advantages of fast and sensitiveness.
