Different combination of antioxidants:a comparative analysis of their antioxidant capabilities
10.7644/j.issn.1674-9960.2015.01.005
- VernacularTitle:不同抗氧化剂配伍组合对抗氧化能力的影响
- Author:
Liu YANG
;
Weiguang LI
;
Ruixue WANG
;
Chenggang ZHANG
- Publication Type:Journal Article
- Keywords:
combined antioxidant;
antioxidant capability;
edaravone;
GSH;
vitamin C
- From:
Military Medical Sciences
2015;(1):22-25,51
- CountryChina
- Language:Chinese
-
Abstract:
Objective To provide reference for clinical application of combined antoxidants , by evaluating the com-bined and individual antioxidant activities of three commonly used antioxidants :edaravone,glutathion(GSH) and vitamin C ( VC) .Methods The multiple and individual antioxidant activities of the three antioxidants were compared by determining total antioxidant activity assay , reductive activity assay , superoxide anion scavenging assay and hydroxyl radical scavenging assay.Results and Conclusion Results showed that the combined antioxidants acted synergistically in scavenging free radicals and increased remarkably antioxidant activity at the same molar concentration .The rationality of different antioxi-dant combination should be taken into consideration in subsequent clinical application .
