Correlation of computed tomography perfusion and Cyfra21-1 in head and neck squamous carcinoma
10.3969/j.issn.1002-1671.2015.07.007
- VernacularTitle:头颈部鳞癌 CT 灌注成像与血清 Cyfra21-1含量的临床相关性研究
- Author:
Jin ZHONG
;
Jun LIU
;
Caixian HAO
;
Liang XU
;
Hui QIAO
;
Xuehuan LIU
;
Changqing ZONG
;
Yi GONG
;
Zhenxing LIU
- Publication Type:Journal Article
- Keywords:
computed tomography;
perfusion;
squamous carcinoma;
Cyfra21-1
- From:
Journal of Practical Radiology
2015;(7):1086-1089,1099
- CountryChina
- Language:Chinese
-
Abstract:
Objective To estimate the value of computed tomography perfusion for clinical stage and approach the correlation of perfusion parameters and Cyfra21-1.Methods 63 patients with head and neck squamous carcinoma were confirmed by pathology and follow up underwent CT perfusion,which were divided into three groups by international clinical staging criteria(stageⅠ,stageⅡand stageⅢ-Ⅳ).BF,BV,MTT,TTP and Cyfra21-1 were recorded and compared with correlation in different clinical staging.Results There was no significant difference of Cyfra21-1 between stageⅠand stageⅡ(Z =1.439,P =0.1 62).There was significant differ-ence of Cyfra21-1 between stageⅠand stageⅢ-Ⅳ(Z =3.356,P =0.000),stageⅡand stageⅢ-Ⅳ(Z =4.959,P =0.000).There was significant difference of BF and BV between stageⅠand stageⅡ,stageⅠand stageⅢ-Ⅳ(P <0.05),of MTT and TTP between stageⅠand stageⅢ-Ⅳ,stageⅡand stageⅢ-Ⅳ(P <0.05).There was no significant difference of BF and BV between stageⅡand stageⅢ-Ⅳ(P >0.05),of MTT and TTP between stageⅠand stageⅡ(P >0.05).Cyfra21-1 and perfusion parameters in all groups have relationship(r=0.76,0.76,-0.82,-0.82,P <0.05).Conclusion The statistically significant of positive correlation be-tween Cyfra21-1 and perfusion parameters in head and neck squamous carcinoma suggests that CT perfusion could play a complemen-tary role in clinical assessment.
