Grading of Uterine Cervical Neoplasms：A Pilot Study with Small Field of View Intravoxel Incoherent Motion MRI Technology
10.3969/j.issn.1005-5185.2015.03.018
- VernacularTitle:小视野体素内不相干运动MRI在宫颈癌术前分级中的可行性
- Author:
Shifeng XIANG
;
Yunyun GAO
;
Lihua ZHANG
;
Ying LI
;
Sujun YANG
;
Xiaolei DONG
- Publication Type:Journal Article
- Keywords:
Uterine cervical neoplasms;
Magnetic resonance imaging;
Diffusion weighted imaging;
Apparent diffusion coefficient;
Pathology,surgical
- From:
Chinese Journal of Medical Imaging
2015;(3):219-221,225
- CountryChina
- Language:Chinese
-
Abstract:
PurposeTo probe into the feasibility of small field of view intravoxel incoherent motion (IVIM) MRI in the grading of cervical cancer before surgery.Materials and Methods Twenty-three patients with cervical cancer confirmed pathologically underwent preoperative conventional MRI and IVIM sequence scan [IVIM sequence included 10 b value (0-1500 s/mm2)]. Based on postoperative pathological cell morphology the patients were divided into well differentiated group (10 cases) and moderately or poorly differentiated group (13 cases). Then the parameters such as the ADC standard, D value, D* value and f value were calculated in each group according to double exponential function analysis. The data in the two groups were compared and nonparametric test to see whether they had normal distribution.Results Compared with the well differentiated group, the moderately or poorly differentiated group had statistically lower ADC standard value and D value (t=140.5 and 129.5,P<0.05); the area under the D value curve was 0.965 and 0.854, respectively. The sensitivity and specificity of well differentiated group and moderately or poorly differentiated group were 88.9%, 100.0% and 77.8%, 81.8%, respectively. There was no difference in either D* value or f value between the two groups (t=-0.184 and 1.072,P>0.05).Conclusion Small field of view IVIM MRI is feasible in predicting the differentiation of tumor in the preoperative grading of cervical cancer.
