The diagnostic value of multi-modal MRI for prostate cancer
10.3760/cma.j.issn.1008-6706.2015.06.009
- VernacularTitle:多模态磁共振成像技术在前列腺癌诊断中的价值
- Author:
Jinjun WANG
;
Xinghua GUO
;
Xiaohong ZHANG
;
Guofang ZHENG
- Publication Type:Journal Article
- Keywords:
Prostatic Neoplasms;
Magnetic Resonance iImaging;
Magnetic Resonance Spectroscopy
- From:
Chinese Journal of Primary Medicine and Pharmacy
2015;(6):825-827,828
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the diagnostic value of multi -modal MRI for prostate cancer .Methods The multi modalitymagnetic resonance data of 43 patients with prostatic diseases were retrospectively analyzed ,selected biopsy or operation pathology results as the control ,analyzed their unenhanced MRI ,DWI,MRS and DCE -MRI. Results (1)In 43 patients,29 cases were diagnosed by biopsy of prostate cancer .37 cancer lesions were found,and 28 cancer lesions showed obviously low signal intensity in T 2WI.(2)The mean ADC value of the cancer lesions and normal areas were (0.69 ±0.09) ×10 -3 mm2/s and (1.31 ±0.18) ×10-3 mm2/s,there was significant difference in ADC value between the two groups (t=21.06,P<0.01);(3) The mean Cho +Cre/Cit value of the cancer lesions and normal areas were (2.67 ±1.58) and (0.74 ±0.28),there was significant difference in ADC value between the two groups (t=7.34,P<0.01);(4)32 rapidly ascending and slowly descending type ROI's,4 flat type ROI's and 1 rising type ROI's were founded in cancer lesions .Conclusion Multi-modal MRI can further provide the blood perfusion of prostate cancer ,water molecule diffusion and microcirculation state ,metabolism and biochemical composi-tion change information .The combination of T2WI,DWI,MRS and DCE-MRI can improve the diagnostic efficiency for the detection of prostate cancer prominently .
