Clinical research of emergency early mechanical ventilation and bronchoalveolar lavage and drug intervention to prognosis of severe asthma
10.3760/cma.j.issn.1008-6706.2015.06.019
- VernacularTitle:急诊早期机械通气联合支气管肺泡灌洗及药物介入治疗对重症哮喘的疗效研究
- Author:
Li CHENG
;
Qiang XU
;
Jian HUANG
- Publication Type:Journal Article
- Keywords:
Mechanical ventilation;
Bronchoalveolar lavage;
Severe asthma;
Efficacy
- From:
Chinese Journal of Primary Medicine and Pharmacy
2015;(6):857-858,859
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical efficacy of emergency early mechanical ventilation and bron -choalveolar lavage and drug intervention to severe asthma .Methods 140 cases with severe asthma were selected ,the patients were divided into the study group and the control group according to a random number table ,70 cases in each group,the control group were received early mechanical ventilation ,the study group were given bronchoalveolar lavage and interventional therapy on the basis of the control group ,clinical efficacy ,alveolar function ,her condition improved and hospital stay of the two groups were compared .Results The total efficiency of the study group were 92.9%(65/70) significantly higher than 81.4%(57/70) in the control group,the difference was statistically significant (χ2 =12.382,P<0.05);Forced expiratory volume in one second (FEV1),forced vital capacity (FVC) and FEV1/FVC of the study group were significantly better than that of the the control group ,the difference was statistically significant ( t=9.098,10.382,11.204,all P<0.05);Condition improved and hospital stay of the study group were significantly shorter than that of the control group,the difference was statistically significant (t=9.898,12.393,all P<0.05). Conclusion Emergency early mechanical ventilation and bronchoalveolar lavage and drug intervention to severe asthma had better clinical efficacy ,which can significantly improve the clinical symptoms of the patient .
