Clinical distribution and drug resistance of 7 315 strains of Enterobacteriaceae bacteria
10.3969/j.issn.1673-4130.2015.06.030
- VernacularTitle:7315株肠杆菌科细菌的临床分布与耐药性分析
- Author:
Gang LI
;
Huizheng ZHAO
;
Wei JIA
;
Mei ZHAO
;
Xiaoyan ZHOU
;
Hong MA
;
Linlin WANG
;
Shasha LI
;
Hui DONG
;
Zhiyun SHI
- Publication Type:Journal Article
- Keywords:
Enterobacteriaceae;
resistance surveillance;
nosocomial infections
- From:
International Journal of Laboratory Medicine
2015;(6):786-787,790
- CountryChina
- Language:Chinese
-
Abstract:
Objective To research the clinical department distribution and drug resistance of Enterobacteriaceae bacteria to pro‐vide a theoretical basis for clinical rational use of antimicrobial drugs .Methods The Whonet 5 .6 software was adopted to conduct the retrospective analysis on Enterobacteriaceae bacteria isolated in the General Hospital of Ningxia Medical University and the Af‐filiated Cardiovascular Disease Hospital from 2011 to 2013 .Results A total of 7 315 strains of Enterobacteriaceae bacteria were i‐solated ;the top three of bacteria were 2 971 strains (40 .6% ) of Escherichia coli ,2 339 strains (32 .0% ) of K lebsiella pneumoniae and 1 117 strains (15 .3% ) of Enterobacter cloacae ;in the source of specimen ,the respiratory tract specimens had the highest isola‐tion rate (46 .6% ,3 410 strains) ,followed by the pus and secretion specimens (13 .9% ,1 015 strains) ,and the urine specimens (13 .0% ,953 strains) ;the isolated bacterial strains were mainly derived from the pediatric department (17 .5% ,1 282 isolates) ,res‐piration department (7 .1% ,518 strains) and ICU (6 .4% ,468 strains) ;the highest sensitivity of antibacterial drugs were carbapen‐ems ,amikacin and piperacillin/tazobactam also maintained a good antibacterial activity ,the resistance rate was 1 .3% - 7 .6% .Con‐clusion Enterobacteriaceae has a higher isolation rate in the clinical specimens and its resistance rates to antibacterial drugs are generally higher .The surveillance on bacterial drug resistance should be strengthened so as to provide a theoretical basis for the ra‐tional use of antimicrobial drugs and effective control of nosocomial infections .
