How to identify the increase of peripheral white blood cells caused by glucocorticoid and infection
10.3969/j.issn.1671-8348.2015.08.021
- VernacularTitle:糖皮质激素与感染造成外周血白细胞计数升高的鉴别
- Author:
Yanhong ZHANG
;
Hui WANG
;
Xuan HU
;
Changyou YUAN
- Publication Type:Journal Article
- Keywords:
glucocorticoid;
count of leukocyte;
percent of neutrophile;
CRP;
morphology of leukocyte
- From:
Chongqing Medicine
2015;(8):1075-1076,1079
- CountryChina
- Language:Chinese
-
Abstract:
Objective To distinguish the increase of white blood cells after glucocorticoid is the adverse reaction of glucocor‐ticoid or infection aggravated .If we can analyse it properly ,the abuse of antimicrobials and waste of medical could be avoid re‐source .Methods 74 patients which were in our hospital from 2011 .1 to 2012 .12 were recruited into this study .They were divided into three groups ,including non‐infection with glucocorticoid(n=15) ,infection without glucocorticoid(n=29) and infection with glucocorticoid(n=30) according to disease and therapies .After being treated 0 day ,3 days ,7 days ,venous blood of patients were collected to detect white blood count ,CRP and morphology of leukocyte .Results The group of non‐infection with glucocorticoid applied glucocorticoid after 3 days and 7days ,WBC was increased significantly(P<0 .01 ,respectively) .And compare with the group of infection without glucocorticoid ,more band neutrophils could be seen in peripheral blood smear of the other two(P< 0 .05) . While there was no difference on level of CRP between the groups of infection without glucocorticoid and infection with glucocorti‐coid(P>0 .05) .Conclusion Glucocorticoid rise the count of WBC in peripheral blood especially the neutrophil .We can evaluate in‐fectious status by the level of CRP and the count of band neutrophils in peripheral blood smear .
