The clinical application value of serum ferritin in acute coronary syndromes
10.3969/j.issn.1671-8348.2015.09.010
- VernacularTitle:血清铁蛋白在急性冠状动脉综合征临床应用研究中的作用
- Author:
Feng PAN
;
Shaoli DENG
;
Zhicheng ZHANG
;
Haihang MA
;
Ming CHEN
- Publication Type:Journal Article
- Keywords:
coronary heart disease;
acute coronary syndrome;
ferritin
- From:
Chongqing Medicine
2015;(9):1184-1185,1188
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship of serum ferritin(SF) and acute coronary syndrome(ACS) .Methods ACS group(n= 110) was divided into unstable angina(UA) subgroup(n= 46) ,non-ST-segment elevation myocardial infarction (NSTEMI) subgroup(n=30) and ST-segment elevation myocardial infarction(STEMI) subgroup(n=34) according to clinical da-ta ,coronary angiography and electrocardiogram examination .The normal coronary patients provided as control group(n=42) .The levels of serum ferritin ,hs-CRP and serum lipids were determined and the differences of SF among the groups were analyzed .The correlation of hs-CRP ,TG ,LDL-C ,HDL-C ,TC and SF were also analyzed .Results Compared with control group ,the level of SF in UA ,NSTEMI ,STEMI were significantly increased(P<0 .05) .Comparison in the levels of SF in NSTEMI ,STEMI group and UA group had significant difference(P<0 .05) .Correlation analysis indicated that the level of SF were positively correlated with hs-CRP ,TG and negatively associated with HDL-C .Conclusion The level of SF significantly increased in patients with ACS and has a positive relationship with hs-CRP and the disorder of lipid metablism .SF helps in assessing the clinical classification and risk strati-fication in patients with ACS .
