Quality Standard for Yangxueyin Oral Liquids
- VernacularTitle:养血饮口服液的质量标准
- Author:
Zhang CHUNYU
;
Zhuang CHENG
;
Shang LIANG
- Publication Type:Journal Article
- Keywords:
Yangxueyin oral liquids;
Quality standard;
TLC;
HPLC-ELSD;
Astragaloside A
- From:
China Pharmacist
2015;(3):506-507,522
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish the quality control for Yangxueyin oral liquids. Methods:TLC was applied to identify Angeli-cae Sinensis Radix and Fructus Ziziphi Jujubae. The content of astragaloside A in Yangxueyin oral liquids was determined by HPLC-ELSD. A Luna C18(250 mm ×4.6 mm,5 μm)column was used, the mobile phase was acetonitrile-water (38∶62)with the flow rate of 0. 8 ml·min-1 , and the column temperature was 40℃. The temperature of the drift tube was 85℃, and the flow rate of the carrier air was 2.0 L·min-1. Results: The linear range of astragaloside A was 0.522-4.176 μg(r =0.999 8). The average recovery was 97. 9% with RSD of 1. 03% (n=6). Conclusion:The method is convenient, sensitive and accurate, which can be used in the quality control of Yangxueyin oral liquids.
