Analysis of the clinical features and prognostic factors of primary thyroid lymphoma

VernacularTitle:甲状腺原发恶性淋巴瘤的临床特点及预后因素分析
Author: Yun HOU ; Huaqing WANG ; Kai FU ; Xianming LIU ; Lihua QIU ; Huilai ZHANG ; Zhengzi QIAN ; Wei LI ; Lanfang LI ; Xishan HAO
Publication Type:Journal Article
Keywords: Thyroid neoplasms; Lymphoma; Prognosis
From: Journal of Leukemia & Lymphoma 2010;19(1):23-25,28
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinical features and prognostic factors of primary thyroid lymphoma. Methods Records of 44 patients with pathologically confirmed primary thyroid lymphoma were reviewed. Detailed clinical and laboratory data were included in univariate analysis, and statistically significant factors in univariate analysis were then included in multivariate analysis.Results In univariate analysis, Ann Arbor stage, performance status, IPI, number of extra-lymphatic site, B symptoms, Hb, LDH and β_2-MG level, therapy model, histology type and tumor mass were found to be the prognostic factors associated with overall survival in primary thyroid lymphoma. In multivariate analysis, performance status, IPI, LDH, β_2-MG level, histology type, and tumor mass were independent prognostic factors of overall survival. Conclusion Performance status, IPI, LDH and β_2-MG level, histology type and tumor mass were demonstrated as independent prognostic factors of the overall survival in primary thyroid lymphoma.