Determination of Impurities in Pharmaceutical Adjuvant Sodium Bisulfite by IC
- VernacularTitle:离子色谱法测定药用辅料亚硫酸氢钠中的杂质
- Author:
Lin PENG
;
Yanming LIU
;
Haiyan LONG
;
Yingying XIE
;
Niancen PENG
- Publication Type:Journal Article
- Keywords:
Pharmaceutical adjuvant;
Sodium bisulfite;
Impurities;
IC
- From:
China Pharmacist
2014;(11):1862-1864,1865
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To determine the impurities in pharmaceutical adjuvant sodium bisulfite. Methods: An IC method was used with a Dionex IonPac AS17-C RFIC analytical column. ECD was used as the detector by gradient elution and the temperature of column was 30℃. Results:Sulfate radical was detected out in all samples. Conclusion:The method is simple and fast with high sensi-tivity, which is suitable for the determination of related substances in sodium bisulfite.
