Effect of Sodium Cantharidate Vitamin B6 Injections in Adjuvant Treatment of Advanced Cervical Cancer
- VernacularTitle:斑蝥酸钠维生素B6注射液辅助治疗晚期宫颈癌疗效观察
- Author:
Hongling JIANG
;
Hui HUANG
- Publication Type:Journal Article
- Keywords:
Sodium cantharidate vitamin B6 injections;
Advanced cervical cancer;
Curative effect;
Immune function
- From:
China Pharmacist
2014;(11):1904-1905,1906
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the effect of sodium cantharidate vitamin B6 injections in the adjuvant treatment of advanced cer-vical cancers. Methods:Totally 60 cases of advanced cervical cancer patients were randomly divided into the observation group and the control group, and the control group was given common DP chemotherapy and radiotherapy, while the observation group was given sodium cantharidate vitamin B6 injections additionally. After the 6-week treatment, the short-term curative effect, bone marrow inhibi-tion adverse reaction, immune function and life quality were compared between the two groups. Results:The short-term curative effect in the observation group was 66. 7%, which was significantly higher than that in the control group (40%)(P<0. 05). The degree of adverse reaction was significantly lower than that in the control group with statistical significance (P<0. 05). After the treatment, CD8 +, NK cells and CD8 + / CD4 + in the two groups were significantly improved, and those in the observation group were all better than those in the control group (P<0. 05). The improvement of life quality in the observation group was more notable than that in the control group with statistical significance (P <0.05). Conclusion: Sodium cantharidate vitamin B6 injections can significantly in-crease the short-term curative effect and immune function, decrease bone marrow inhibition and improve life quality of advanced cervi-cal cancer patients.
