Comparison of HBsAg Results between Roche Cobas e601 and Abbott Architect i2000 analysis systems
10.3969/j.issn.1673-4130.2014.20.044
- VernacularTitle:罗氏 Cobas e601与雅培 Architect i2000检测乙肝表面抗原的比较
- Author:
Bin SUN
;
Kang LI
;
Chun WU
;
Fengjie GUO
;
Guangliang BAI
;
Mei DONG
- Publication Type:Journal Article
- Keywords:
HBsAg;
electrochemiluminescence immunoassay;
chemiluminescent microparticle immunoassay
- From:
International Journal of Laboratory Medicine
2014;(20):2823-2824,2851
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the difference of the HBsAg detected results between the Roche cobas e601 electrochemilumi-nescence immunoassay instrument and the Abbott Architect i2000chemiluminescent microparticle immunoassay instrument.Methods The HBsAg positive specimens with the quantitation results of lower than 250IU/mL detected by the Abbott Architect i2000 were selected and simultaneously detected by the Roche cobas e601.The differences of detected results were compared and per-formed the linear correlation and analysis regression.Results 46 clinical specimens were detected.The detected results had best correlation between the two instruments by getting rid of 1 specimen with unconformable reactivity of detected results.15 speci-mens had the HBsAg detected result of 0.05-1.00 IU/mL by the Abbott Architect i2000,the linear regression equation was Y =17.49X+0.843(r=0.979);15 specimens had the HBsAg detected result of 1.1 -10.00 IU/mL IU/mL by the Abbott Architect i2000,the linear regression equation was Y =15.72X +21.06(r=0.952);15 specimens had the HBsAg detected result of 11 -250 IU/mL by the Abbott Architect i2000,the linear regression equation was Y =29.17X -129(r=1.000).Conclusion The detected results have better correlation between the two instruments and can be mutually converted by the formulas.