The effect of sevoflurane pretreatment or aftertreatment on intrapulmonary shunt for patients with one lung ventilation during thoracic surgical procedures
10.3969/j.issn.1671-8348.2014.30.003
- VernacularTitle:七氟烷预处理或后处理对胸外科手术单肺通气患者肺内分流的影响
- Author:
Hongqin ZHANG
;
Diping WANG
;
Ping LI
;
Wei XIAO
;
Lu XU
- Publication Type:Journal Article
- Keywords:
sevoflurane;
one lung ventilation;
intrapulmonary shunt;
thoracic surgical procedures
- From:
Chongqing Medicine
2014;(30):3991-3993,3996
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of sevoflurane pretreatment or aftertreatment on intrapulmonary shunt for patients with one lung ventilation(OLV)during thoracic surgical procedures .Methods 80 ASA I or II patients underwent thoracic surgery with OLV were randomly divided into four groups(n= 20 for each):(1)Propofol group(group P);(2)Sevoflurane pretreatment group(group S1);(3)Sevoflurane aftertreatment group(group S2);(3)Sevoflurane whole-treatment group(group S3) .Blood sam-ples were taken from radial artery and right atrial blood before induction of anesthesia(baseline T .0) ,before OLV(sevoflurane pre-treatment 30 min ,T1) ,after OLV 30 ,60 min and before the end of OLV(T2-T4)and after the end of OLV(T5)for measurement of blood gases and calculation of Qs/Qt .The indexs of hemodynamics and relative clinical data were recorded .Results Arterial oxy-gen pressure of the four groups for OLV significantly reduced ,when compared with double lung ventilation(P<0 .05) ,but there was no significant difference among the four groups(P>0 .05) .Intrapulmonary shunt of the four groups for OLV significantly in-creased ,when compared with double lung ventilation(P<0 .05) ,but intrapulmonary shunt of S1 ,S2 and S3 groups significantly de-creased ,when compared with P group ,and there was no significant difference for S1 ,S2 and S3 groups(P> 0 .05) .Conclusion Sevoflurane can decrease intrapulmonary shunt for patients during OLV ,but there is no significant difference for pretreatment or af-tertreatment or whole treatment and do not increase arterial oxygen pressure .
