Comparative study on inflammation stress reaction between laparoscopic operation and open operation in treating hysteromyoma
10.3969/J.ISSN.1672-8270.2014.11.041
- VernacularTitle:腹腔镜下手术与开腹手术治疗子宫肌瘤术后炎性应激反应的对比研究
- Author:
Cailan RONG
;
Chunyan TANG
- Publication Type:Journal Article
- Keywords:
Hysteromyoma;
Laparoscopic operation;
Inflammation reaction
- From:
China Medical Equipment
2014;(11):111-113,114
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the inflammation stress reaction between laparoscopic operation and open operation in treating hysteromyoma.Methods: hysteromyoma patients in our hospital from January 2011 to December 2012 were enrolled and randomly divided into observation group given laparoscopic operation and control group given open operation. Then inflammatory factors levels were detected, operation trauma index were observed and the correlation were analyzed.Results: (1)After treatment, inflammatory factor levels of two groups were higher than those before treatment and IL-1(t=5.892,P<0.05), TNF-α(t=11.842,P<0.05)levels of observation group were lower than control group, the difference was statistical significance(P<0.05); (2) There was no significant difference between two groups of operation time(t=0.932,P>0.05), intraoperative bleeding volume(t=7.842,P<0.05), postoperative anal exhaust time(t=7.283,P<0.05), bed time(t=8.213,P<0.05) and NRS pain scores(t=7.883,P<0.05) of observation group were lower than control group(P<0.05); (3) Intraoperative bleeding volume, postoperative anal exhaust time, bed time and NRS pain scores were positively correlated with IL-1,r2 were separately 0.485, 0.521, 0.442, 0.451; and positively correlated with TNF-α levels,r2 were separately 0.556, 0.513, 0.423, 0.458, the difference was statistical significance(P<0.05).Conclusion: Laparoscopic operation is helpful to reduce the operation wound and relieve postoperative inflammatory reaction; and there was close correlation between inflammatory stress and operation trauma.
