Yiyuan Shengjing Decoction Treat Similar Climacteric Syndrome of Breast Cancer after Treated with Tamoxifen
- VernacularTitle:益元生精汤治疗乳腺癌三苯氧胺治疗后类更年期综合征的临床观察
- Author:
Yunfu SHI
;
Qiaoling WEI
;
Lina ZHOU
- Publication Type:Journal Article
- Keywords:
Yiyuan Shengjing Decoction;
breast cancer;
endocrinotherapy;
tamoxifen;
similar climacteric syndrome
- From:
Journal of Zhejiang Chinese Medical University
2014;(10):1172-1174,1182
- CountryChina
- Language:Chinese
-
Abstract:
Objective] To observe the clinical effect of Yiyuan Shengjing Decoction on similar climacteric syndrome of breast cancer after treated with tamoxifen. [Method] Choose 60 cases of breast cancer, randomly divide them into control group 30 cases and treatment group 30 cases, the control one were treated with tamoxifen and oryzanol, the treatment one, with tamoxifen and Yiyuan Shengjing Decoction. After 4w, evaluate the efficacy, compare their clinical symptoms score, hormone levels and endometrium thickness, and calculate the clinical relieving rate. [Result] After treatment, both groups clinical symptoms were relieved more than before treatment, with difference of statistical meaning; comparing on clinical symptoms scores, the treatment was much less than control one, with statistical meaning; on clinical relieving rates, the treatment group reached 83.33%, while 26.67% for control one, both had difference of statistical meaning. The comparison of reproductive hormone levels and endometrium thickness, the difference had no statistical meaning. [Conclusion] Yiyuan Shengjing Decoction treating breast cancer similar climacteric syndrome after treated with tamoxifen had marked cure effect, without influencing reproductive hormone level and endometrium thickness.
