Clinical feature and drug resistance of multi-drug resistant Acinetobacter baumanii in hospital

VernacularTitle:医院感染多重耐药鲍曼不动杆菌临床特征及耐药性分析
Author: Fengqi WU ; Baoying JIN
Publication Type:Journal Article
Keywords: Acinetobacter baumannii; anti-bacterial agents; Drug resistance; multi-drug resistance
From: Chinese Journal of Primary Medicine and Pharmacy 2014;(22):3448-3449,3450
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinical feature of Acinetobacter baumannii and to provide the basis for clinical rational use of anti-microbial agents.Methods ATB system was used to identify Acinetobacter baumanii, and antimicrobial resistance was determined by Kirby-Bauer method.The results were analyzed by Whonet 5.4 soft-ware.Results A total of the 358 strains Acinetobacter baumannii were isolated,91.62% were from sputum and throat swab.The main departments was ICU(52.23%);In 358 strains Acinetobacter baumannii,217 strains were multi-drug resistant strains(60.61%).The drug resistance to polymyxin B was the lowest 0% followed by minocy-cline 19.8% and cefoperazone/sulbactam 9.8%, the next was netilmicin 21.1% and meropenem 41.5%. Conclusion Acinetobacter baumannii shows multi-drug resistance, especially in ICU.Anti-microbial agents should be the rational use according to the results of drug susceptibility in order to reduce and control the incidence of noso-comial infections.