Comparison of the effects of continuous renal replacement therapy and hemodialysis in the treatment of acute renal failure
10.3760/cma.j.issn.1008-6706.2014.21.011
- VernacularTitle:连续性肾脏替代治疗与血液透析对急性肾功能衰竭的疗效比较
- Author:
Aixia YANG
- Publication Type:Journal Article
- Keywords:
Renal Replacement Therapy;
Hemodiafiltration;
Acute Kidney Injury
- From:
Chinese Journal of Primary Medicine and Pharmacy
2014;(21):3228-3229,3230
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the effects of continuous renal replacement therapy and hemodialysis in the treatment of acute renal failure.Methods 70 patients with acute renal failure were selected and randomly divided into A group and B group according to the wishes of patients.The patients of A group were given continuous renal replacement therapy,the patients of B group were given hemodialysis.APACHE-II scoring system were used,the clini-cal efficacy,adverse reactions,serum creatinine,urea nitrogen,APACHE-II score,the duration of urine more than 600mL were compared.Results The clinical effective rate of A group was 65.7%,which was significantly higher than 54.3%of B group(χ2 =11.321,P<0.05);The serum creatinine and urea nitrogen of A group were (198.1 ± 20.5)μmol/L,(20.3 ±2.6) mmol/L,respectively,which were lower than (283.3 ±19.3)μmol/L,(28.3 ± 1.5)mmol/L of B group,the duration of urine more than 600mL of A group was (12.1 ±0.7)d,which was lower than (18.3 ±2.1)d of B group,APACHE-II score of A group was (14.1 ±2.1)points,which was lower than (17.5 ±1.9) score of B group,the difference was statistically significant( t=12.023,11.321,10.983,9.985,all P<0.05);The incidence of adverse reactions of A group were 5.7%,which was lower than 17.1% of B group(χ2 =12.174,P<0.05).Conclusion The continuous renal replacement therapy and hemodialysis had advantages in treatment of sever acute renal failure,but continuous renal replacement therapy had better clinical results,and fewer adverse reactions.
