Comparative study on difference of procalcitonin level between serum and plasma in children
10.3969/j.issn.1673-4130.2015.01.030
- VernacularTitle:儿童血清与血浆中降钙素原水平差异比较研究
- Author:
Jie WEN
;
Wenling LI
;
Junna ZHOU
;
Liang LI
;
Rui HUANG
;
Lei ZHU
- Publication Type:Journal Article
- Keywords:
children;
serum;
plasma;
EDTA-K2;
procalcitonin
- From:
International Journal of Laboratory Medicine
2015;(1):71-72,74
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the difference of procalcitonin (PCT)level between serum and plasma in children so as to in-vestigate whether ethylenediamine tetraacetic acid dipotassium (EDTA-K2 )anti-coagulation plasma could replace serum to be an al-ternative material for PCT testing.Methods The PCT concentrations in the serum and EDTA-K2 anti-coagulation plasma from 90 children patients were detected by using the mini-VIDS-GB automatic enzyme linked fluorescence analyzer and the plasma PCT au-tomatic quantitative detection method.The correlation between the two sets of data was analyzed.And the data were assigned into the 3-level groups for conducting statistic analysis.At the same time the influence of child′s age and gender on the PCT level was al-so discussed.Results The PCT level in serum was well correlated with that in EDTA-K2 anti-coagulation plasma (r=0.812,P <0.05).There were no statistically significant differences in PCT levels between serum and plasma measured in the low level groups (P >0.05).However,the differences of the PCT levels between serum and EDTA-K2 anti-coagulation plasma in the middle level group and high level group were statistically significant (P <0.05).Child′s gender and age have significant effect on the PCT level. Conclusion There is statistically significant difference between serum and plasma PCT detection levels in children,which has an important guiding role for further systematic study of PCT level difference in serum and EDTA-K2 anticoagulation plasma and its clinical significance.
