Analysis on correlation between multiple biochemical indicators and T2DM complicating gout
10.3969/j.issn.1673-4130.2015.01.038
- VernacularTitle:多种生化指标与2型糖尿病合并痛风的相关性分析
- Author:
Aixia HUANG
- Publication Type:Journal Article
- Keywords:
diabetes complicating gout;
uric acid;
high density lipoprotein cholesterol;
low density lipoprotein cholesterol;
high sensitive C reactive protein
- From:
International Journal of Laboratory Medicine
2015;(1):89-90,92
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the correlation between the levels of uric acid(UA),plasma total cholesterol(TC),triglyceride (TG),high density lipoprotein cholesterol(HDL-C),low density lipoprotein cholesterol (LDL-C),lipoprotein A(LPL)and hyper-sensitive C-reactive protein(hs-CRP)with type 2 diabetes mellitus(T2DM)complicating gout.Methods The levels of UA,TC, TG,HDL-C,LDL-C,LPL and hs-CRP in the T2DM complicating gout group,the T2DM without gout group and the gout group were measured and statistically analyzed to evaluate whether the differences of these indicators among 3 groups having statistical significance.Results Compared with the T2DM without gout group,the TG,LDL-C,hs-CRP and UA levels in the T2DM compli-cating gout were increased (P <0.05),while the HDL-C level was decreased(P <0.05).Ccompared with the gout group,the GLU, TG,LDL-C,LPL,hs-CRP and UA levels in the T2DM complicating gout group were significantly increased (P <0.05 )and the HDL-C level was decreased(P <0.05).The UA level in the T2DM complicating gout group was positively correlated with GLU, TC,TG,LDL-C,LPL and hs-CRP levels(P <0.05),the correlation coefficient were 0.313,0.283,0.422,0.297 and 0.436 respec-tively,which was negatively correlated with HDL-C(P <0.05),the correlation coefficient was -0.523.Conclusion The UA,TC, TG,HDL-C,LDL-C,LPL and hs-CRP levels have close correlation with T2DM complicating gout,detecting these biochemical indi-cators is helpful to monitor and control the occurrence and the development of T2DM complicating gout.
