Complement system and tumor:research progress Complement system and tumor:research progress
10.13220/j.cnki.jipr.2014.05.002
- VernacularTitle:补体系统与肿瘤的关系研究进展
- Author:
Chang NING
;
Wenwei CHEN
;
Yan LI
;
Guojiang CHEN
- Publication Type:Journal Article
- Keywords:
complement;
tumor;
growth factor;
signal pathway;
angiogenesis
- From:
Journal of International Pharmaceutical Research
2014;(5):516-520,521
- CountryChina
- Language:Chinese
-
Abstract:
Complement system is an important component of innate immunity and has been recognized as an effective means to inhibit tumor. However,in last decades,accumulating studies showed unexpected results that the complement components and their activation products could promote development of malignancies by secreting growth factors,activating signal pathway and promoting tumor angiogenesis. Herein,the relationship between the complement system and tumor is reviewed.