Establishment of Conformity Test Model for Tamsulosin Hydrochloride Sustained-release Capsules by NIR
- VernacularTitle:盐酸坦洛新缓释胶囊近红外一致性检验模型的建立
- Author:
Bin LI
- Publication Type:Journal Article
- Keywords:
Tamsulosin hydrochloride sustained-release capsules;
NIR;
Conformity test
- From:
China Pharmacist
2014;(12):2138-2139,2142
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish the conformity test model for tamsulosin hydrochloride sustained-release capsules by near infrared absorption spectroscopy. Methods:Tamsulosin hydrochloride sustained release capsules were scanned within the range of 4 200-12000 cm-1 to establish the conformity test model. Results:The spectral coverage of 9 000-7 500 cm-1 , 6 900-5 600 cm-1 and 5 000-4 250 cm-1 were chosen, and the second derivative vector normalization was used to detect the samples. The CI value was 7. The conformity test model could distinguish authentic and false tamsulosin hydrochloride sustained-release capsules. Conclusion:The method is simple, sensitive, accurate and fast, and can be used in the identification of tamsulosin hydrochloride sustained-release capsules.
