Rheumatoid arthritis associated with myelodysplastic syndrome: a case report.
10.3346/jkms.1999.14.3.319
- Author:
Eon Jeong NAM
1
;
Young Mo KANG
;
Hye Ryun KANG
;
Jae Han KIM
;
Hyun Joo RHO
;
Myoung Kwon LEE
;
Sang Hoon HYUN
;
Gun Woo KIM
;
Jong Myoung LEE
;
Nung Soo KIM
Author Information
1. Department of Internal Medicine, School of Medicine, Kyungpook National University, Taegu, Korea.
- Publication Type:Case Report
- Keywords:
Myelodysplastic syndromes;
Rheumatoid arthritis
- MeSH:
Adult;
Arthritis, Rheumatoid/radiography;
Arthritis, Rheumatoid/pathology;
Arthritis, Rheumatoid/complications*;
Arthritis, Rheumatoid/blood;
Case Report;
Female;
Follow-Up Studies;
Human;
Myelodysplastic Syndromes/pathology;
Myelodysplastic Syndromes/complications*;
Myelodysplastic Syndromes/blood
- From:Journal of Korean Medical Science
1999;14(3):319-322
- CountryRepublic of Korea
- Language:English
-
Abstract:
Myelodysplastic syndromes (MDS) are a group of refractory anemias resulting from a clonal stem cell disorder often associated with cytogenetic abnormalities. There is increasing recognition of immunological abnormalities in patients with MDS, including defective B- and T-cell function, hyper- or hypogammaglobulinemia and monoclonal gammopathy. MDS have been associated with Sjogren's syndrome, polymyalgia rheumatica, relapsing polychondritis and systemic lupus erythematosus. Although there may be various rheumatologic features, including acute arthritis in MDS, chronic inflammatory arthritis is uncommonly combined. There have been a few reports that described cases of rheumatoid arthritis (RA) concurrent with MDS, but advanced rheumatoid arthritis with typical joint deformities has rarely been reported. We report a case of rheumatoid arthritis with atlantoaxial subluxation combined with refractory anemia in a 31-year-old woman.
