Analysis on clinical infection distribution and drug resistance of 442 strains of Escherichia coli
10.3969/j.issn.1673-4130.2014.23.025
- VernacularTitle:442株大肠埃希菌临床感染分布及耐药性分析
- Author:
Xuelian FANG
;
Haiviao LIN
;
Huilun HUANG
;
Shuyuan WANG
;
Zhaoxin LAI
;
Shaokui TAN
;
Yongzhong RONG
;
Jianving WANG
- Publication Type:Journal Article
- Keywords:
Escherichia col i;
extended-spectrumβ-lactamases;
drug resistant;
rational drug use
- From:
International Journal of Laboratory Medicine
2014;(23):3210-3211,3214
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical infection distribution and drug resistance status of 442 strains of Escherichia coli to provide the basise for the treatment of Escherichia coli infection and the control of nosocomial infection.Methods The clinically submitted various kinds of specimens during 2013 were performed the bacterial culture and identification.The susceptibility of Escherichia coli to commonly used bacterial drugs were detected by adopting the MIC method.The data were analyzed by WHO-NET V5.5 and SPSS V13.0 softwares.Results 442 strains of Escherichia coli were isolated from the middle urine and secretion. The detection rate of ESBLs-producing Escherichia coli was 61.3%.442 strains of Escherichia coli had the high resistance to peni-cillins,cephalosporins and fluoroquinolones,better sensitivity toβ-lactam/β-lactamase inhibitor compounds and highest sensitivity to carbapenems.ESBLs-producing Escherichia coli had the higher resistance to commonly used antibacterial drugs than non-ESBLs-producing Escherichia coli .Conclusion The drug resistance of Escherichia coli is severe.ESBLs-producing Escherichia coli are u-sually resistant to many different types of antimicrobial drugs.Carbapenems are the first choice to treatment of severe infections of Escherichia coli .
