Comparative Study of Focal Pulmonary Ground Glass Nodule Between Findings of High Resolution CT and Pathology Classiifcation of IASLC/ATS/ERS
10.3969/j.issn.1005-5185.2014.11.004
- VernacularTitle:肺局限性磨玻璃结节的高分辨率CT征象与国际肺癌研究协会/美国胸科学会/欧洲呼吸学会病理的对照研究
- Author:
Feng PAN
;
Zhuo LIU
;
Fei YUAN
;
Jun WANG
;
Kunkun SUN
;
Xiangke DU
;
Nan HONG
- Publication Type:Journal Article
- Keywords:
Coin lesion,pulmonary;
Lung neoplasms;
Adenocarcinoma;
Tomography,spiral computed;
Pathology,surgical
- From:
Chinese Journal of Medical Imaging
2014;(11):815-819,823
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To evaluate the correlations between high resolution CT (HRCT) findings and IASLC/ATS/ERS pathological classification of ground glass nodule (GGN). Materials and Methods 121 patients with confirmed GGN were selected, and divided into benign group (22 cases), PIL group (21 cases), microinvasive carcinoma group (26 cases) and invasive carcinoma group (52 cases), then the imaging, pathology and prognosis data of patients with pulmonary GGN were reviewed, and the differences among GGN of different pathological types were analyzed.Results Maximum diameter, margin, vacuole sign, solid component, shape and blood vessels through of GGN were significantly different among the four groups (χ2=9.945-31.068,P<0.05). Maximum diameter and margin were significantly different between invasive adenocarcinoma and other groups (P<0.008); vacuole sign of the benign group was significantly different with other groups (P<0.008); the existence of solid component and shape were significantly different between invasive adenocarcinoma and minimally invasive adenocarcinoma (P<0.008); there was significant difference of blood vessels through between invasive adenocarcinoma and benign lesions (P<0.008). Among the 121 lesions, no metastasis except one invasive adenocarcinoma case complicated with distant metastasis.Conclusion Maximum diameter of GGN greater than 16.35 mm, with spiculation or lobulation represent invasive adenocarcinoma; vacuole sign within the GGN represent malignancy; with solid component and irregular shape can be used to identify invasive adenocarcinoma from minimally invasive adenocarcinoma; while blood vessels through can be used to identify invasive adenocarcinoma from benign lesions; the prognosis of GGNs is well with only 0.83% probability of distant metastasis.
