The analysis ofβ-lactam antibiotics interference in fructosamine testing
10.3969/j.issn.1673-4130.2014.22.041
- VernacularTitle:临床常用β-内酰胺类抗菌药物对果糖胺检测的干扰分析
- Author:
Wei YAN
;
Jing ZHOU
;
Wenjuan YAO
;
Ran CHENG
;
Xiaoming YAO
- Publication Type:Journal Article
- Keywords:
cephathiamidine;
ticarcillin;
clavulanate;
fructosamine;
interference
- From:
International Journal of Laboratory Medicine
2014;(22):3097-3098,3101
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the interference of 13 kinds of β‐lactam antibiotics in fructosamine detection .Methods A se‐ries of solution of antimicrobial drugs were formulated with water for injection ,and added into the mixture fresh serum volume by 5% .Interfere with antimicrobial drugs on the test results of fructosamine were evaluated .Results When the blood concentrations of cefathiamidine and ticarcillin sodium/clavulanate potassium were up to 37 .5 mg/L and 247 .5 μg/mL respectively ,they began to produce positive interference on fructosamine detection .However ,the degree of interference was not correlated to the serum concen‐tration of fructosamine .Conclusion Cephathiamidine and ticarcillin sodium/clavulanate potassium have positive interference on fructosamine detection .
