The clinical value of Sharp-van der Heijde score in rheumatoid arthritis

VernacularTitle:类风湿关节炎 Sharp-van der Heijde 评分的临床应用价值
Author: Weihong HE ; Weizhi WU ; Lei LEI ; Zhiying HE
Publication Type:Journal Article
Keywords: anti-cyclic citrullinated peptide antibody; radiography; rheumatoid arthritis
From: Journal of Practical Radiology 2014;(11):1865-1867,1875
CountryChina
Language:Chinese
Abstract: Objective To evaluate the clinical value of Sharp-van der Heijde score (SHS)in rheumatoid arthritis (RA).Methods Clinical and X-ray of hands data in 200 patients with RA met the ACR criteria were collected in this study.Clinical DAS28,anti-cyclic citrullinated peptide antibody (aCCP)and imaging SHS were used to evaluate the activity of RA quantitatively before and after treatment.Results A moderate correlation existed between SHS and DAS28 (r s =0.61,P =0.00),but there was no significant cor-relation either between SHS and aCCP (r s = -0.1 5,P =0.03)or between aCCP and DAS28 (r s =0.14,P =0.05 ).Significant differences before and after treatment was existed in SHS (t=24.27,P =0.00)and DAS28 (t=1 5.98,P =0.00)respectively.And there was a moderate correlation between the difference in SHS before and after treatment and aCCP (r s =0.66,P =0.00).Conclu-sion The SHS,DAS28 and the aCCP in RA are closely related.Combination of three methods will help to develop the clinical pro-grams,evaluate the efficacy and prognosis.