Three-dimensional Speckle Tracking Echocardiography for Evaluating Cardiac Function in Breast Cancer Patients Treated with Anthracycline
10.3969/j.issn.1005-5185.2014.10.006
- VernacularTitle:三维斑点追踪成像评价乳腺癌患者蒽环类药物化疗后的心脏功能
- Author:
Shuai ZHANG
;
Xiaohong XU
;
Kang ZHANG
;
Lijuan LIU
;
Jun XIE
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Surgical procedures;
Drug therapy;
Anthracyclines;
Echocardiography,three-dimensional;
Speckle tracking imaging;
Ventricular function,left
- From:
Chinese Journal of Medical Imaging
2014;(10):745-748,753
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To investigate the value of three-dimensional speckle tracking echocardiography in evaluating the cardiac function in breast cancer patients treated with Anthracycline. Materials and Methods Thirty-two breast cancer patients were followed with three-dimensional echocardiography prechemotherapy (group A), 2 cycles (group B) and 4 cycles (group B) postchemotherapy to compare left ventricle global longitudinal strain (GLS), global radial strain (GRS), global circular strain (GCS), global area strain (GAS), early diastolic global area strain rate (EASR), and early diastolic 3D velocity (3DVe). Results GCS, GAS and EASR were signiifcantly lower in group C than group A (t=3.555, 3.692 and 3.590, P<0.01);EASR was lower in group B than group A with statistical significance (t=2.190, P<0.05). GLS, GRS and 3DVe were not significantly different among three groups (F=2.305, 1.957 and 1.205, P>0.05). EASR was negatively correlated with IVRT (r=-0.44, P<0.01); EASR was positively correlated with Em (r=0.49, P<0.01) and Em/Am (r=0.32, P<0.01). GSR was positively correlated with Sm (r=0.21, P<0.05). Conclusion Three-dimensional echocardiography sensitively detects the early changes in diastole function in breast cancer patients treated with Anthracycline.
