Diagnostic therapy and safety assessment of tulobuterol tape in suspected wheezing children
10.3969/j.issn.1671-8348.2014.36.018
- VernacularTitle:妥洛特罗贴剂对疑似喘息儿童的诊断性治疗及安全性评价
- Author:
Hong ZHANG
;
Xia CHEN
;
Xiaoxi CHEN
;
Hongzhen XU
- Publication Type:Journal Article
- Keywords:
asthma;
child;
bronchodilator;
diagnosis;
treatment
- From:
Chongqing Medicine
2014;(36):4906-4908,4913
- CountryChina
- Language:Chinese
-
Abstract:
Objective To conduct the diagnostic treatment in the children under 5 years old with suspected asthmatic disease and to evaluate its safety .Methods The children outpatients with suspected asthmatic diseas were selected and divided into the experi‐mental group and the control group according to odd days and even days .The conventiona therapy of anti‐infection ,relieving cough , reducing sputum and supporting treatment were administered in both groups .The experimental group was added tulobuterol tape . The cough relieve on daytime and nighttime ,initial effective time ,cough disappearance time and occurrence rate of adverse events at 24 ,72 h and on 5 d after treatment were compared between the two groups .Results The total effective rate of cough sysmptom re‐lief in the experimental group at 3 time points and nighttime was higher than that in the control group with statistical difference be‐tween the two groups(P < 0 .05) .The initial effective time had no statistically significant difference in daytime between the two groups(P> 0 .05) ,but which in daytime showed the statistically significant difference (P < 0 .05) ,especially the cough disappear‐ance time at nighttime in the experimental group was significantly shortened than that in the control group( P < 0 .05) .The oc‐curence rate of adverse events had no statistical difference between the two groups(P > 0 .05) .Conclusion Tulobuterol tape by transdermal delivery as one of diagnostic treatment measures for children under 5 years old with suspected asthmatic disease is defi‐nitely effective ,safe and convenient in application with the high compliance for children patients and acceptability by the family members ,obviously shortens the course of treatment ,which is worthy of being promoted .
