Establishment and ultrasonic evaluation of rabbit abdominal aorta atheromatous plaque
10.3969/j.issn.1671-8348.2014.36.023
- VernacularTitle:兔腹主动脉粥样斑块的建立与超声评价
- Author:
Yong ZHANG
;
Yongping LU
;
Hong ZHOU
;
Yuan YUAN
;
Yueyue TANG
;
Rui LIU
;
Yunyan LI
;
Lirong XU
- Publication Type:Journal Article
- Keywords:
rabbit;
abdominal aorta;
atheromatous plaque;
ultrasound
- From:
Chongqing Medicine
2014;(36):4922-4923,4927
- CountryChina
- Language:Chinese
-
Abstract:
Objective To prepare the rabbit abdominal aorta atheromatous plaque model ,and to monitor its forming process by ultrasound .Methods Totally 60 Japanese male white rabbits(mdel group ,dead 6 rabbits) fed by high fat diet and the abdominal a‐orta atheromatous plaque formation process was monitored by ultrasound ,20 normal rabbits were taken as control .The abdominal aorta atheromatous plaque was finally confirmed by pathology .Results 52 rabbits in the model group were successful in preparing the abdominal aortic plaque model .The thickness of intima‐media complex was obviously higher than that of the control group .Con‐clusion High fat diet is an effective method for preparing the rabbit atherosclerosis model .The arterial atheromatous plaque forma‐tion is the typical characteristic of atherosclerosis .The high frequency ultrasound can better evaluate the formation process and con‐dition of rabbit abdominal aorta atheromatous plaque .
