Experience of surgical treatment for autoimmune hepatitis complicated with cirrhosis and hyper-splenism
10.3969/j.issn.1005-6483.2014.12.014
- VernacularTitle:自身免疫性肝炎后肝硬化伴脾功能亢进外科手术治疗体会
- Author:
Zuoyou WU
;
Hai DING
- Publication Type:Journal Article
- Keywords:
autoimmunehepatitis;
hypersplenism;
livercirrhosis
- From:
Journal of Clinical Surgery
2014;(12):914-915,916
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of splenectomy on autoimmune hepatitis complicated with cirrhosis and hypersplenism.Methods Nine cases of autoimmune hepatitis complicated withcirrhosis and hypersplenism were treated with splenectomy and periesophagogastric devascularization.Results All patients recovered well.Their liver functions recovered to the preoperative level within twoweeks after operation.No significant differences were found between preoperative and postoperative levelsof transaminase and bilirubin(P >0.05).The count of leukocyte and platelet rose to the normal level andthere were significant differences between the preoperative and postoperative levels(P <0.05).Patients'symptoms of hypersplenism were corrected and their coagulation function improved significantly (P <0.05).Conclusion In patients with autoimmune hepatitis complicated with cirrhosis and hypersplenism,splenectomy with periesophagogastric devascularization is an effective procedure for improving hypersplenism,enhancing blood coagulation,and reducing bleeding.