The study of visual pathway of gloucoma patients with DTI
10.3969/j.issn.1002-1671.2014.12.003
- VernacularTitle:青光眼视通路白质纤维束的 DTI 初步研究
- Author:
Haijie ZHANG
;
Xuelin ZHANG
;
Guoxiong LI
;
Lixuan XIE
;
Zhongquan LI
;
Weiwei LIU
- Publication Type:Journal Article
- Keywords:
diffusion tensor imaging;
visual pathway;
glaucoma
- From:
Journal of Practical Radiology
2014;(12):1962-1965,1970
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the microstructural characteristics of white matter fiber tracts of visual pathways using diffusion tensor imaging (DTI)in the patients with primary glaucoma.Methods Twenty patients with primary bilateral glaucoma and 30 nor-mal adults were recruited and scanned with visual pathways magnetic resonance imaging (MRI)and DTI,obtaining T1 FLAIR ima-ges and directionally encoded color (DEC)images.On DEC images,ROIs were put in the anterior,middle and posterior part of bi-lateral optic nerve,optic tract and optic radiation,to calculate the average FA and MD value of each region.Results T1 FLAIR and DEC images could clearly show the optic nerve,optic tract and optic radiation.In patients with glaucoma,the FA values of optic nerve,optic tract and optic radiation were:0.372±0.040,0.340±0.036,0.31 5±0.026,while the MD values were:1.760±0.1 1, 1.831±0.09,1.927±0.10.The FA values of optic nerve,optic tract and optic radiation of normal adults were:0.538 ±0.073, 0.460±0.082,0.455±0.083,whilst the MD values were:0.995 ±0.27,1.312 ±0.40,1.347 ±0.37.Compared with the normal controls,FA values of all parts are deceased whereas the MD values of all parts are increased in patients.Conclusion Glaucoma is a central nervous system disease involving the whole visual pathways.Use DTI can evaluate the microstructural characteristics of white matter fiber tracts of visual pathways in the patients with glaucoma.
