MRI diagnosis of sellar germ cell tumors
10.3969/j.issn.1002-1671.2014.12.005
- VernacularTitle:鞍区生殖细胞肿瘤的 MRI 诊断
- Author:
Junrong LI
;
Jianhong ZHAO
;
Junlin ZHOU
;
Yongjun LUO
;
Chengkui CHAI
;
Jun ZHAO
- Publication Type:Journal Article
- Keywords:
intracranial;
germ cell tumors;
magnetic resonance imaging;
pathology
- From:
Journal of Practical Radiology
2014;(12):1971-1973,2009
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the MRI features of germ cell tumors in sellar regions for better developing clinical treatment plans.Methods The imaging and pathologic findings of 44 sellar germ cell tumors were retrospectively analyzed.Results There were 1 9 germinoma,most of which had clear boundaries,different extents of cystic necrosis and mild peritumoral edema.Lesions were significantly enhanced in contrast-enhanced MRI (CE-MRI).There were 8 cases with mature teratoma,most showed cystic-solid changes,presenting mixed-intensities on T1-weighted images and T2-weighted images.There were 1 1 malignant teratoma(im-mature teratoma and teratoma malformation ),however,there were more parenchymatous tissue in malignant teratoma than mature teratoma.Two yolk sac tumors showed uniform signals on T1-weighted images and T2-weighted images,significant enhancement on CE-MRI,and visibly higher AFP in serum.Two embryonal carcinomas had clear boundary,inhomogeneous intensities,visibly cyst-ic necrosis,median to servere peritumoral edema,the parenchyma showed significant enhancement in CE-MRI.The signals of two mixed germ cell tumors were not typical,which depended on the components within tumors.Conclusion The MRI features of germ cell tumors in sellar region are characteristic.
