Research on effect of rt-PA thrombolytic therapy on elderly patients with cerebral infarction
10.3969/J.ISSN.1672-8270.2014.12.051
- VernacularTitle:重组人组织型纤溶酶原激活剂溶栓治疗高龄脑梗死患者的临床价值
- Author:
Xia ZHOU
;
Cheng ZHANG
- Publication Type:Journal Article
- Keywords:
Infarction;
Recombinant tissue plasminogen activator;
Thrombolysis;
Advanced age
- From:
China Medical Equipment
2014;(12):136-138,139
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To analyze the Effect of rt-PA thrombolytic therapy on elderly patients with cerebral infarction. Methods: Chosen elderly patients with cerebral infarction between November 2012 to November 2013 as study object, randomly divided into observe group receive rt-PA thrombolytic therapy and control group receive aspirin and Batroxobin, detecting neurological impairment, physical function score and adverse treatment outcomes. Results: 1)before thrombolytic treatment, neurological deficit situation of two groups were no significant difference (P>0.05), after treatment, observation group patients’ neurological deficit scores were significantly lower than control group at each time point (P<0.05); 2)after treatment, limb function defective number of observation group patient was significantly less than observation group(P<0.05); 3)after treatment, observation groups’ adverse outcomes as again infarction, large area cerebral hemorrhage after thrombolysis, plant survival, incidence of death was significantly lower than control group (P<0.05). Conclusion: The injection of rt-PA thrombolytic therapy can significantly optimize neurological and physical function in patients , reducing the incidence of adverse treatment outcomes, with positive clinical significance.
